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There have also been mixed outcomes from trials with regard to the utility of TMB. Up to now, no potential clinical trials experienced shown that choice of ICI treatment dependant on a substantial TMB above small TMB increases OS.1,10 Most experiments have evaluated TMB in certain tumors types, While KEYNOTE-158 evaluated TMB retrospectively in 10

There have also been mixed effects from trials concerning the utility of TMB. To date, no prospective scientific trials experienced demonstrated that variety of ICI cure according to a substantial TMB over lower TMB improves OS.one,10 Most scientific tests have evaluated TMB in certain tumors forms, While KEYNOTE-158 evaluated TMB retrospectively i

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